CD28 anticorps

N° du produit ABIN610016

L’anticorps Souris Monoclonal anti-CD28 a été validé pour FACS, ELISA et Func. Il convient pour détecter CD28 dans des échantillons de Humain.

Aperçu rapide pour CD28 anticorps (ABIN610016)

Antigène: CD28

Fragment: F(ab')2 fragment

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD28 est non-conjugé

Application: Flow Cytometry (FACS), ELISA, Functional Studies (Func)

Clone: ANC28-1-5D10

Détail du produit anti-CD28 anticorps

Specificité: CD28 expressed on T cells and also on BHK cells transfected with human CD28. This antibody has been characterized as a superagonist.

Purification: Gel filtration

Immunogène: Recombinant Human CD28 and HPB-MLT human tumor cells.

Type of Immunogen: Recombinant protein

Isotype: IgG1 kappa

Information d'application

Indications d'application: Approved: ELISA, Flo, Func

Usage: Function: ANC28.1 stimulates expression of IL-2 from CD28+ cells. Divalent ANC28.1 can induce Antigen Independent T cell proliferation. In combination with anti-CD81 mAb, it can prime naive T cells to acquire effector function independent of TCR ligation. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Not recommended for: WB

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride

Conseil sur la manipulation: Do not freeze. Open under aseptic conditions.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze. Open under aseptic conditions.

Détails sur CD28

Antigène: CD28

Autre désignation: CD28

Sujet: Name/Gene ID: CD28

Synonyms: CD28, CD28 antigen, CD28 antigen (Tp44), Tp44, CD28 Molecule

ID gène: 940

UniProt: P10747

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response